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However, the company may submit new premarket tobacco product applications (PMTAs) for the products subject to these MDOs

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24-h urine volume, 1900 mL

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"Cigarette smoking, even experimentally, among children of any age should be strongly discouraged." The research, published Wednesday in the Journal of the American Heart Association, uses information from children and adolescents who were ages 6 to 19 in the 1970s to 1980s, with follow-up information from many of them as recently as 2018