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Sometimes laser ablation, surgical resection, or embolization of symptomatic arteriovenous malformations Supplemental iron therapy Possibly blood transfusions Sometimes antifibrinolytic drugs (eg, aminocaproic acid, tranexamic acid) Sometimes angiogenesis inhibitors (eg, bevacizumab, pomalidomide, thalidomide) Treatment for most patients is supportive, but accessible telangiectasias (eg, in the nose or gastrointestinal tract via endoscopy) may be treated with laser ablation
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Increased flux through the mevalonate pathway mediates fibrotic repair without injury
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