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Over time, due to the release of large amounts of serotonin, nicotine causes a significant depletion of the neurotransmitter thus leading to negative psychological aftermaths

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Prof Sir Ian Gilmore Chair, Alcohol Health Alliance

The criteria set for the replication were (i) the same direction of effect as the discovery analysis and (ii) P 0.0045 in the replication studies (Bonferroni-adjusted for eleven SNVs at = 0.05)

He puts it elegantly, with logic that is difficult to deny, if one accepts that consumers are making at least semi-rational choices about personal benefit rather than bowing to the whims of fiends