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In KoGES, the general population aged 4069 years was targeted to collect epidemiological data as well as biospecimens, including blood, urine, and DNA by conducting a large-scale survey on health and lifestyle habits and performing health screening 21

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These beneficial effects may additionally be mediated via the 7 nicotinic receptor as this receptor subtype also enhances the antidepressant effects of serotonin uptake blockers (75)

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