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Data were extracted on: study aims and design

Therefore, the San Francisco YRBSS data preceded the flavor ban enforcement and should not be used to conclude that the ban was associated with increased youth smoking

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Acknowledgements We acknowledge Dr Martin Figeac from the Functional and Structural Platform (CHU Lille, France) for transcriptomic analyses and Dr OLivier Molendi-Coste and Hlne Bauderlique from the Bicell platform (Universit de Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41UAR 2014PLBS, 59000 Lille, France) for the flow cytometry analysis