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A typical one-pack-daily smoker receives about 100,000 reinforcing hits a year, much more than with cocaine or heroin (Brunton, 1999)

Within the U.S., the Transportation Security Administration (TSA) does not currently restrict oral nicotine products

In value terms, the market is forecast to increase with an anticipated CAGR of +4.0% for the period from 2024 to 2035, which is projected to bring the market value to $30M (in nominal wholesale prices) by the end of 2035

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When nicotine-b-cyclodextrin complex dissolved, free nicotine was released from the tablet formulation and penetrated through the oral mucosa (58)