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Clinical observational studies have consistently revealed strong associations between laryngeal cancer and smoking, particularly long-term and heavy smoking, but whether smoking is the primary etiological factor for laryngeal cancer remains incompletely understood 30

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Production was gradually standardized, and the brand became associated with consistent quality rather than innovation-driven change

Restricting all cigarette sales or menthol cigarette sales in that way also may have the largest effect on the total direct and indirect costs of cigarettes