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"Nicotine is the chemical that makes cigarettes addictive

These organisations also clarify that while nicotine is addictive, it is not directly responsible for the harmful effects or cancer caused by smoking

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A 2014 study by the CDC revealed a significant uptick in nicotine vape pen-related calls to poison control centers the number of calls increased from one per month in September 2010 to 215 per month in February 2014, while the number of calls involving cigarettes remained steady over that time

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