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The assumption is that since nicotine is the addictive component in cigarettes, introducing a product that has 25 times less nicotine than a traditional cigarette would lead to less nicotine dependence

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doi:10.1016/S0749-3797(02)00420-8

Each SNP has three regression results: one unadjusted for smoking status, one adjusted for NLP-derived smoking status, and the other adjusted using ICD-defined smokers

Also, it truly is a practicable alternative to have it directly from your cigarette corporations