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One non-randomized open-label study, published over 2 separate articles, showed that 4-week liraglutide led to an improvement in a test of executive functioning (and possibly other cognitive measures) 178 and related increase in fronto-striatal volumes 179 , partly moderated by BMI and insulin resistance changes, in 19 people diagnosed with bipolar disorder or major depression

Acknowledgements This work was supported by the NIA (R00AG037574 and R56AG052981), the Prevent Cancer Foundation, the American Institute for Cancer Research (AICR), the American Federation for Aging Research (AFAR) and Einstein Startup Funds to D.M.H

Further, a vitamin B12 deficiency was associated with lower levels of glutathione in the blood, according to a 2017 study in Molecular Neurobiology

According to public reports, the clinical trial version of the new drug failed to help participants lose more weight than those who took Zepbound