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The compounds research-only status reflects the absence of completed human clinical trials rather than a determination that it is inherently dangerous a distinction that is important for interpreting its regulatory position accurately

Their results indicated a significant reduction in the frequency and duration of the migraine attacks, migraine days per month, and the amount of acute migraine medication (83)

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The trial product (primary) estimand evaluated the treatment effect for all randomised participants under the assumption that all participants continued taking the trial product for the entire planned duration of the trial and did not use rescue medication