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First, the total daily dose in international units (TDD) is calculated by multiplying body weight in kilograms by 0.3 to 0.5 international units (IU)

These benefits were further supported by the results of the SUMMIT trial, which investigated tirzepatide, a dual GLP-1/glucose-dependent insulinotropic polypeptide receptor agonist, in patients with HFpEF with or without T2D

The deal is expected to close later this year, and excludes rights previously sold by GSK (in the US, Australia and Germany)

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