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Pharmacogenetics cohorts and methods Response to GLP-1RA and other oral hypoglycemic agents (DPP-4i, metformin and sulfonylurea) were compared between carriers and non-carriers of PAM p.S539W and p.D563G carriers

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4 Thiamine metabolism in intestinal cells 4.1 Thiamine transport in brush border and basolateral membranes of enterocytes Due to its hydrophilic nature, thiamine is not membrane-permeable, with its entry into the cell depending on membrane proteins dedicated to thiamine transport

To problem nie tylko indywidualny, lecz take systemowy