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She didn't think quitting the drugs would be that big of a deal: She had lost as much as she wanted to, and in her mind, the company's messaging throughout her two years had suggested that, "unless you were a diabetic, there was no need to stay on the GLP-1." But Isherwood told Fortune that within six to eight months, she gained back about 20 pounds as she reverted to old behaviors when stressors arose in her lifea familiar pattern that she'd experienced before

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Caan BJ, Cespedes Feliciano EM, Prado CM, et al

Protecting muscle matters more than adherence to a fasting protocol