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169 In a recent randomized trial, 1 year of combined GLP-1 therapy with exercise training preserved bone mineral density, while GLP-1 therapy alone decreased bone mineral density

[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Alam M.M., Rivero-Navea G., Rivero-Jimenez R.A

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102 Compared with the structure of human GLP-1(7-36), the amino acid sequence of albiglutide contains an arginine at position 8 (in GLP-1, this residue is lysine), and two modified GLP-1 peptide chains are fused to human serum albumin (HSA), thereby greatly extending its half-life