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The SM1 voxel was centered on the right central sulcus, posterior to the hand-knob(Yousry et al., 1997) in the axial plane and rotated to align with the cortical surface(Puts et al., 2011)

12 , 13 Moderate physical activity and healthy diets promote a balanced microbiome (eg, a high Bacteroidetes to Firmicutes ratio) along with the production of neurotransmitters (eg, serotonin, dopamine), secondary bile acids, and short-chain fatty acids, including acetate, propionate, and butyrate (Figure 1)

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We may suggest only one injection in a month for more than 6 months if one/two injections per week in the initial period show a remarkable improvement