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Pinnamaneni P, Kantarjian H, Jorgensen JL, Jabbour E, Pierce S, Brandt M, Wang S, Konopleva M, Kornblau S, Kadia T, DiNardo C, Pemmaraju N, Andreeff M , Estrov Z, Garcia-Manero G, Cortes J, Ravandi F

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Here we show that a single administration of GLP-1 or GLP-1MK-801 elicits comparable reductions in the blood glucose levels in DIO mice, whereas equimolar MK-801 monotherapy does not acutely affect glycaemia (Fig

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Using ER stress inducers and diet-induced NASH in mice, we investigated the molecular mechanism by which ER stress leads to impaired CMA activity and hepatic lipid accumulation