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Clinical data from the SURMOUNT-1 trial published in the New England Journal of Medicine demonstrated dose-dependent weight loss: 16% average body weight reduction at 5mg, 21.4% at 10mg, and 22.5% at 15mg over 72 weeks

Taken together, PDL9 chondrocytes contained significantly more senescent cells than PDL3 chondrocytes, confirming that extensive in vitro expansion led to chondrocyte senescence

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Hers is also not available in every state for GLP-1 prescriptions specifically

The primers used in this study are listed in Table S3