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Inflammation is a hallmark of ASD, with elevated levels of IL-1, IL-6, IL-8, IL-12, IL-17, IFN-, and TNF- in plasma and serum samples [316,317,318]

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A45 is enrolling 1,000 cognitively healthy participants with positive amyloid PET scans, and they will receive lecanemab titrated to 10 mg/kg every 2 weeks for 96 weeks, followed by 10 mg/kg every month through week 216