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pros: - very hydrating - stays on

Naturally occurring carnitine plays a key role in this process, as well as helping to clean out cellular waste so that the body can work more efficiently

While the nephroprotective effects of SGLT2i were initially derived from secondary endpoints of CV outcome trials (CVOTs), direct confirmation came from dedicated kidney focused trials: CREDENCE (Perkovic et al NEJM 2019| NephJC Summary), DAPA-CKD (Heerspink et al NEJM 2020| NephJC Summary) and finally EMPAKIDNEY (Herrington et al NEJM 2023| NephJC Summary)

Infections may also contribute to HT via molecular mimicry, in which structural or amino acid sequence similarities between microbial and human antigens induce cross-reactive immune responses, accelerating the development of autoimmunity (da Silva et al

Cummings J, Lee G, Ritter A, Sabbagh M, Zhong K