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As a GLP-1 receptor agonist, semaglutide works by mimicking the incretin hormone GLP-1

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7 biggest news story of 2025: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), in widespread use to treat diabetes and obesity, have also demonstrated off-label benefits for a multitude of conditions, including cardiovascular disease, hypertension, Parkinsons, Alzheimers and some addictive disorders