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MS spectra were acquired between 3501,250 m/z (molecular weight/valency) in high-resolution mode (40,000 resolution for full scans and 20,000 resolution for MS/MS scans) with a rolling collision energy using a 250 ms accumulation time/spectrum and 50 mDa mass tolerance, and the 10 most intense precursors per cycle were selected for fragmentation with a dynamic exclusion time of 30 s

In silico analyses using ADPredict (Lo Monte et al, 2018) and DeepSADPr (Sha et al, 2022) tools predicted that potential 16 PARylated sites of RSMC are enriched coincidentally within the two dispersed Sororin-interacting motifs (SIM) (Fig

Intravenously administered glutathione ensures 100% absorption

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While liposomal glutathione is a potent tool for neutralizing oxidative stress and supporting detoxification, it is not a standalone cure