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Patients with type 2 diabetes or obesity who meet criteria for GLP-1 therapy may experience additional lipid benefits, particularly those with mixed dyslipidaemia, metabolic syndrome, or established cardiovascular disease

5,6 Nutrients associated with GLP1 secretion are monosaccharides, long-chain fatty acids and short-chain fatty acids (from bacterial fiber fermentation)

The main drug class of GLP-1 receptor agonist is liraglutide, dulaglutide, lixisenatide, and others

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However, in our study, oxidative stress-induced cell death was triggered by lipid peroxidation instead of the canonical mitochondrial ROS accumulation