This can be risky for patients, as unapproved versions do not undergo FDAs review for safety, effectiveness and quality before they are marketed
Seek urgent same-day assessment or call 999 for emergency care if experiencing: Severe chest pain Severe shortness of breath Fainting or collapse Acute or rapidly worsening neurological deficits (such as new limb weakness, sudden gait disturbance, or bladder/bowel dysfunction) Persistent or worsening anaemia symptoms despite treatmentincluding breathlessness, chest discomfort, palpitations, or extreme fatigueshould trigger medical review
Dosing Schedule Administration : Once-weekly injection under the skin (subcutaneous)
this results in reduced transcription of mitochondrial ribosomal proteins and mitochondrial transcription factors, and subsequently halting protein translation 101,102
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