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Bradbury JA, Danjoux JP, Voller J, Spencer M, Brocklebank T (1991) A randomised placebo-controlled trial of topical cysteamine therapy in patients with nephropathic cystinosis

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IGF-1 Elevation: Full GH therapy consistently elevates IGF-1 levels, which concerns oncologists due to potential proliferative effects on existing cancers

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Beyond race and ethnicity, other aspects of diversity that need to be better represented in clinical trial populations include sex and geography (e.g., rural, suburban, and urban), as well as socioeconomic status and social phenotypes