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In 1968, in response to a few athlete deaths that were believed to be linked to P.E.D

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no MHRA or NICE guidance exists yet, as the drug remains investigational pending phase 3 results

Clinical trials of the safety and effectiveness of Melanotan are ongoing, but in 2008 the European Medicines Agency approved a blend of the peptide called Scenesse to be marketed for limited prescription-only use by those with specific skin conditions throughout the European Union