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Cuff MA, Lambert DW, Shirazi-Beechey SP

One-month-old MPS VI rats are given once weekly sc injections of Pentosan Polysulfate (1, 2 and 4 mg/kg, human equivalent dose (HED)), or daily oral Pentosan Polysulfate (4 mg/kg HED) for 6 months

As we refine our knowledge about microbiota-RT interactions, microbiome modulation strategies are poised to play a key role in personalized oncology radiation treatments

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Identification of ICAT as an APC inhibitor, revealing Wnt-dependent inhibition of APC-axin interaction