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Prep details matter because false results are commonrecent antibiotics, probiotics, laxatives, or diet changes can skew outcomes, and constipation can alter timing

Overall, our data suggest that systemic administration of SEM, initiated on the same day as OHT was induced, does not prevent the OHT-associated RGC-loss, but delays the magnitude of IOP increase, delays or partially prevents astrocyte remodeling, and provides mild vasoprotection

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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