This deficiency can arise from various factors, including inadequate dietary intake, impaired absorption, or certain medical conditions
Populations at a higher risk of vitamin B12 deficiency include people who are vegetarian or vegan, exclusively breastfed infants of vegan women, older adults, those with gastrointestinal disorders or who have had gastrointestinal surgery, and people with an autoimmune condition known as pernicious anemia
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By selectively inhibiting NNMT an enzyme central to energy regulation and fat metabolism this compound has demonstrated, in preclinical studies, the capacity to elevate intracellular NAD and SAM levels, suppress lipid accumulation in adipocytes, and reduce white adipose tissue mass in diet-induced obese mouse models
Furthermore, methylcobalamin is important in treating peripheral neuropathy, and diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis