The Postpartum Weight Loss Dilemma The challenge: Many women are eager to restart GLP-1s after delivery
However, genetic deletions of GLP-1Rs in various hypothalamic regions, including the paraventricular nucleus (PVN), arcuate nucleus (Arc), or ventromedial nucleus of the hypothalamus, do not impair the anorectic effects of peripherally administered GLP-1R agonists (17, 18)
While GLP-1s clearly are effective for weight loss, experts may be concerned if their patients do not make other lifestyle changes, for example, changing their diet or being more active
Successful integration of GLP-1 medications into your life begins with thoughtful scheduling
Dual agonists typically target GLP-1R, GIP (glucose-dependent insulinotropic polypeptide) or IGF (insulin-like growth factor) receptors, while triple agonists target GLP-1R, GIPR, and the glucagon receptor (GCGR)