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These presentations may indicate conditions requiring investigation, including thyroid disorders, cardiovascular issues, pancreatitis, gallbladder disease, or other endocrine abnormalities

Mikus, D., Grabarevic, Z., Rucman, R., Petek, M., Turkovic, B., Rokotov, D

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Imbalances between glutamate and GABA, which are strongly implicated in neuropsychiatric disorders like MDD [77], can lead to excitotoxicity, whereby excessive glutamate activation of NMDARs and AMPARs triggers calcium overload, oxidative stress, and cell death [78]