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Federal law prohibits Medicare from covering drugs solely for weight loss, meaning GLP-1s are only reimbursed under Part D for other approved indications, like type 2 diabetes, cardiovascular risk reduction, MASH, or sleep apnea

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As obese humans show lower circulating glucagon-like peptide-1 (GLP-1), similar to that of PYY, it has been thought that the resistance to this gut hormone contributes to the obesity

Epidemiology 33 , 563571 (2022)

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