This protective effect was achieved by mitigating oxidative stress and apoptosis, promoting angiogenesis, and triggering the GSH-Px antioxidant pathway, thus defending against ischemia-reperfusion brain injury (Kong et al., 2017) (Figure 11)
Early intervention is critical to slowing and reversing the degenerative process
Groups such as the American College of Medical Genetics have issued guidelines recommending against testing for one of these gene mutations
PubMed Wadden, T.A., Chao, A.M., Machineni, S., Kushner, R.F., Ard, J., Srivastava, G., et al
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