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Functional sepiapterin reductase is a homodimeric enzyme which first converts 6-pyruvoyltetrahydropterin to 1-hydroxy-2-oxopropyltetrahydropterin, which is then reduced to 1-oxo-2-hydroxypropyltetrahydropterin, and then finally to 5,6,7,8-tetrahydrobiopterin, BH 4

Available: [Accessed: 16-Aug-2020]

Experts say there are plausible albeit unconfirmed explanations, noting for example that GLP-1 medications may interfere with the efficacy of oral contraceptives or increase fertility in women because they help with weight loss