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Activation of UCP1, a proton channel in the inner mitochondrial membrane of brown adipocytes, produces a leak in the mitochondrial membrane and uncouples ATP synthesis from respiration, thereby dissipating energy as heat (6, 100)
It is not only studied because it is popular online
Several groups have profiled gene expression in patients with and without COPD or between patients with varying levels of airflow obstruction in order to understand differences in gene expression related to COPD [611]
Seiwerth et al., Frontiers in Pharmacology (2021) and Xing et al., Int J Mol Sci (2021)
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