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Upon activation, NLRP3 engages the scaffold protein NIMA related kinase 7 (NEK7) and recruits the adaptor apoptosis-associated speck-like protein containing a CARD (PYD and CARD domain containing (PYCARD, also known as ASC)) to assemble the inflammasome complex

The results showed that GST-EGFP-GPI DAF and GST-EGFP-GPI CEAM7 exhibited the highest enrichment fold in both K-562 and Lenti-X 293T cells (Figures 4A,B)

Conflict of Interest The authors have declared no conflicts of interest

J.PanY.GriffithsB

Start your intake Common Drug Interactions with Glutathione Supplementation Glutathione may interfere with chemotherapy efficacy, particularly alkylating agents and platinum-based drugs