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Eaton JK, Furst L, Ruberto RA, Moosmayer D, Hilpmann A, Ryan MJ, et al

The ammonium ion could be generated from several amino acids or other nitrogen-containing compounds that undergo deamination in extra-hepatic tissues

This is relevant not only for side effect management but for fertility: dutasteride is contraindicated in women of childbearing age and in men who may be trying to conceive, given its effects on DHT-dependent fetal development

People who are concerned about their low level of energy should be advised that unless they already suffer from a vitamin B12 deficiency, there is no strong evidence to support the notion that taking large doses of vitamin B12 will increase their energy levels

Still, GLP-1s may also exert anti-inflammatory effects on the central nervous system, reducing brain inflammation, which has been linked with depression and anxiety, Grawert said