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In the Phase 2 clinical trial published in The New England Journal of Medicine in 2023, gastrointestinal side effects affected the majority of participants, with nausea, vomiting, diarrhea, and constipation being the most frequent complaints

Compounding has a long history in healthcare and was the standard for preparing medicine before large-scale pharmaceutical manufacturing began

PMID 18277970

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These antioxidant enzymes activated by Nrf2 act as cell defense system to detoxify NAPQI [35]