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The adjustment is based on type 2 diabetes risk, not weight alone

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The extent and pattern of depigmentation vary from person to person, with some individuals experiencing small localized patches, while others may have widespread loss of pigmentation across large areas of the body

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Additionally, in phase 2 studies in people with MASH and liver fibrosis, survodutide not only significantly improved liver steatosis, but also led to histologic improvement of MASH without worsening fibrosis in 4362% of participants, versus 14% with placebo [41]