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10.1038/jcbfm.2009.200 18 GargiuloS.GramanziniM.MegnaR.GrecoA.AlbaneseS.ManfrediC.et al (2014)

This means you will draw a larger volume for the same mcg dose, which can make accurate measurement easier and reduce the margin for error, especially for new researchers

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Epigenetic effects include modulation of chromatin structure and DNA methylation, promoting access to beneficial genes while repressing harmful ones