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Within laboratory and preclinical models, it enables investigation of receptor activation mechanisms, pathway modulation, and signal-transduction dynamics without any clinical or therapeutic intent

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Transient hypertension found in the SATO subset of CVS should be treated with short-acting ACE inhibitors (e.g., captopril) during the episode only

LPS promotes the activation of microglia and induces depressive-like symptoms, while treatment with anti-inflammatory medication alleviates depressive symptoms (92, 93)

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