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Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Set Variation Analysis (GSVA) analysis revealed significant activation of the glutathione metabolism pathway in drug-resistant breast cancer tissues compared to sensitive tissues after FEC (5-Fluorouracil, Epirubicin, and Cyclophosphamide) + docetaxel treatment (Fig

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The resulting leaky gut then perpetuates systemic inflammation that further suppresses the immune response against Candida a self-reinforcing cycle that must be broken simultaneously from both ends

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Ilic et al., 2011a), duodenum (Sikiric et al., 1994