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They hypothesized that metabolic and mitochondrial pathways were implicated in the reversal of graying hair, meaning the process could be targeted with pharmacological drugs

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In addition, the lower mRNA expression levels of Bax and P53 and the higher expression levels of Bcl2 and Bcl-xL were detected in the peroxynitrite + ebselen group compared with the peroxynitrite-only group, while the lack of GPX1 in SGNs from gpx1 / mice led to an opposite pattern (Figure 8D)

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