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Dedicated randomized trials examining atrial fibrillation risk with GLP-1 therapy would provide clearer answers

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However, in highly invasive breast cancer cell lines MDA-MB-231 and MDA-MB-468, high concentrations (100 nM) of liraglutide promote breast cancer progression by activating GLP-1R via the NOX4/ROS/VEGF signaling pathway [18]

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& Zhou, L

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Subgroup analyses by drug type, duration of treatment, and patient characteristics similarly showed no concerning signals

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10.1038/s41569-021-00566-9 89 WildingJ

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