The absorption rate constant (Ka) describes the rate of drug absorption into the central compartment
These individuals were compared with matched control participants who had diabetes or obesity but no documented history of substance use disorders
E., Tajiri, N., Kaneko, Y., & Freeman, T
The picture is complicated by several confounding factors: Weight loss itself is associated with improved mood and reduced depressive symptoms in many individuals Better glycaemic control may enhance overall wellbeing and reduce diabetes-related distress Selection bias may exist, as patients with severe mental health conditions might be less likely to be prescribed these medications initially Currently, there is no official indication for GLP-1 agonists in treating depression, and the MHRA has not licensed these medications for mental health conditions
For a supplement working through metabolic pathways rather than stimulant effects, thats exactly how it should work