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Concentration considerations Nasal spray devices typically deliver 100 microliters (0.1 mL) per actuation

No large-scale trials have examined probiotics specifically with GLP-1 receptor agonists like semaglutide

CT, P = 0.024)

Materials and methods Search strategy This systematic review and meta-analysis were performed and reported in accordance with the Cochrane Collaboration Handbook for Systematic Review of interventions and the Preferred reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) [5] Statement guidelines