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Jais, A
Adding GIP receptor (GIPR) agonism introduces a second incretin pathway that enhances insulin secretion through distinct cAMP signaling, independently modulates adipocyte lipid handling, and engages central appetite circuits through complementary routes to GLP-1R
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Seek medical advice if hiccups persist for more than 48 hours, significantly interfere with daily activities, or occur alongside severe abdominal pain, persistent vomiting, or difficulty swallowing
This is why healthcare professionals carefully monitor patients during dose escalation and why any side effects experienced may persist even after stopping the initial dose
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