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A supplementary application for the 9 mg dose has been accepted for review by China NMPA, based on the GLORY-2 results showing 20% weight loss

Therefore, it is recommended to quit smoking and completely limit alcohol consumption during treatment at least

In addition, a high AHI leads to decreased oxygen saturation, which increases cardiovascular stress [56] and may also induce chronic inflammation, insulin resistance, and endocrine changes that affect metabolic function [57]