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Although the major direct physiological effects of ghrelin are exerted within the central nervous system, which in turn affects processes in numerous organ systems, there are direct effects of ghrelin in many of the same organ systems

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There are six main IGF binding proteins in circulation (IGFBP-1 through IGFBP-6), plus several membrane-anchored forms

Sepsis is a systemic inflammatory response caused by excessive cytokine secretion, such as interleukin (IL)-6, IL-10, IL1 and TNF-

doi: 10.1016/j.jneuroim.2008.12.002 146 MorganJTChanaGPardoCAAchimCSemendeferiKBuckwalterJet al