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First, if the contact is directed through the center of mass of the brain (i.e., is centroidal), there may be linear motion and no rotation of the head (e.g., a weight dropping down onto the top of the head or a blow to the back of the head that moves the ears and nose forward without neck flexion or extension)

Based on the phase 2 and phase 3 trial protocols: Weeks 1-4: 1 mg once weekly Weeks 5-8: 2 mg once weekly Weeks 9-12: 4 mg once weekly Weeks 13-16: 8 mg once weekly Weeks 17 onward: 12 mg once weekly (maximum dose) The starting dose of retatrutide is deliberately low because the triple-agonist mechanism produces more intense initial side effects than single-pathway compounds

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He came to us after unsuccessful physiotherapy sessions